Mesothelioma is a cancer associated with exposure to asbestos

Mesothelioma is a cancer associated with exposure to asbestos. Once a realatively obscure disease that meant little to the general public, mesothelioma is now known to be among the most aggressive and difficult to treat tumors oncologists yet have encountered.

The disease most often affects men between the ages of 50 and 70

Statistics show that, because of their work history, the disease most often affects men between the ages of 50 and 70 who were employed in an asbestos-laden environment before asbesto regulations were imposed in the late 1970s. Though women still have a much lower frequency of the disease, cases of second-hand exposure to asbestos has prompted more diagnoses among women, especially those whose male family members worked with asbestos.

Diagnosing mesothelioma

Diagnosing mesothelioma in its early stages can be a challenge even for the most experienced oncologists. Also referred to as asbestos cancer, this rare and aggressive disease is directly related to asbestos exposure. Mesothelioma affects the tissue that surrounds the lungs, heart and abdominal cavity.

Medical professionals and research scientists

Medical professionals and research scientists, however, are constantly exploring new ways to combat the disease. For example, doctors know that some combinations of chemotherapy drugs work better than others and tests developed to ascertain earlier diagnosis of the disease or to monitor those most at risk have arrived on the scene.

Medical professionals and research scientists

Medical professionals and research scientists, however, are constantly exploring new ways to combat the disease. For example, doctors know that some combinations of chemotherapy drugs work better than others and tests developed to ascertain earlier diagnosis of the disease or to monitor those most at risk have arrived on the scene.

The reason someone develops mesothelioma

The reason someone develops mesothelioma is usually the lack of proper protection offered to those who worked with asbestos. Though the dangerous properties of asbestos and asbestos products have been evident for decades, many employers neglected to protect their workers from inhaling asbestos while on the job.

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THURSDAY, Feb. 2 (HealthDay News) -- A warning to certain types as those Super Bowl parties approach: People with a need to please others are more likely to eat too much in social situations, a new study suggests.

"People pleasers feel more intense pressure to eat when they believe that their eating will help another person feel more comfortable," study lead author Julie Exline, a psychologist at Case Western Reserve University, said in a university news release. "Almost everyone has been in a situation in which they've felt this pressure, but people pleasers seem especially sensitive to it."

But there's an emotional cost to this behavior, according to the report published in the current issue of the Journal of Social and Clinical Psychology.

"Those who overeat in order to please others tend to regret their choices later. It doesn't feel good to give in to social pressures," Exline said.

The study included 101 college students who completed a questionnaire that assessed their characteristics for having a people-pleasing personality, such as putting others' needs before their own, worrying about hurting others and being sensitive to criticism.

Each of the participants was then seated alone with a female actor who posed as another study volunteer. The actor was given a bowl of candy and took a small handful (about five pieces) before offering the bowl to the study participant.

Being a people pleaser was associated with taking more candy, both in the laboratory experiment and in a second study involving the participants' recollection of real-life eating situations.

People pleasers "don't want to rock the boat or upset the sense of social harmony," Exline explained.

-- Robert Preidt MedicalNewsCopyright © 2012 HealthDay. All rights reserved. SOURCE: Case Western Reserve University, news release, Jan. 31, 2012



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THURSDAY, March 15 (HealthDay News) -- An electronic diary program helped improve overweight and obese adults' adherence to a weight-loss regimen, according to a new study.

The study included 210 overweight or obese adults who were asked to keep track of aspects of weight-loss treatment such as attendance at group sessions and energy and exercise goals.

The participants kept track using either a paper diary, a personal digital assistant (PDA) without feedback, or a PDA with a program that provided personalized dietary and exercise feedback messages.

The participants who received the feedback messages (one per day on diet and one every other day on exercise) were more successful in attending group sessions, meeting daily calorie goals, meeting daily fat-intake goals, reaching weekly exercise goals and monitoring their eating and exercise.

After six months, people in the group that received feedback messages saw weight loss of more than 5 percent. After 24 months, however, weight loss was similar in all three groups, according to the study, which is scheduled to be presented Thursday at an American Heart Association (AHA) meeting in San Diego.

"The results suggest that using an electronic diary improves treatment adherence," study author Lora Burke, a professor of nursing and epidemiology at the University of Pittsburgh in Pennsylvania, said in an AHA news release.

"Over time, participants' adherence declined, particularly in the later phase as contact frequency declined and subsequently ended," she said. "Adherence in the paper-diary group declined more than in the device groups."

Because this study was presented at a medical meeting, the data and conclusions should be viewed as preliminary until published in a peer-reviewed journal.

-- Robert Preidt MedicalNewsCopyright © 2012 HealthDay. All rights reserved. SOURCE: American Heart Association, news release, March 15, 2012



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By Amanda Gardner
HealthDay Reporter

WEDNESDAY, March 21 (HealthDay News) -- The costs of the obesity epidemic to the United States and the economic value of curbing it are not captured fully by current methods, according to a new report.

The problem is that estimates used by Congress when it looks at these issues project out only 10 years, while it may take much longer than that for complications of obesity, such as diabetes and heart disease, to manifest, the report authors say.

For example, "a person with diabetes is not going to go on dialysis right away. They're going to go on dialysis 10 to 12 years after their diagnosis," said Michael O'Grady, co-author of the report, released Wednesday by the Campaign to End Obesity.

A 25-year window for making policy decisions would be more appropriate when drafting policies aimed at curbing disease, he said at a Wednesday morning press conference.

By the same token, measures to prevent obesity can take 20 or more years, perhaps even generations, to show their promise, the report said. A wider time window would enable policy makers to assess the cost-effectiveness of preventive programs, the report noted.

"Interventions aimed at children will not have their full payoff until those children are adults," said Dr. James Marks, senior vice president and director of the Health Group at the Robert Wood Johnson Foundation, which funded the study.

Nor will the success of interventions aimed at pregnant women be seen for many years, noted the study's authors, speaking at the briefing.

O'Grady, citing current CDC figures, said more than one-third of U.S. adults are overweight, another one-third are obese and 6 percent are extremely obese.

"That's right around three-quarters of the population," said O'Grady, a senior fellow for health care research at the National Opinion Research Center at the University of Chicago and a principal with O'Grady Health Policy, LLC.

One estimate puts the annual cost of obesity at $147 billion, representing almost 10 percent of all medical expenses, the report said. But the Society of Actuaries -- which adds in lost productivity, employees on full disability and absenteeism -- puts the costs closer to $300 billion a year.

And at a minimum, the Congressional Budget Office predicts that per-person, obesity-related spending will increase an average of 3.6 percent a year, the report said.

The authors are asking those who make up budgets, including the Congressional Budget Office, to take into account a growing body of scientific literature on the toll of diabetes as well as hopeful interventions when they tally the price of obesity.

A window of 25 years will help policy makers arrive at more accurate long-term estimates, they said.

"Ten years is adequate for food stamps and aircraft carriers, but there are certain policy areas where we know the disease has a 20- to 25-year progression. You need the flexibility to go beyond 10 years," O'Grady said. "We probably want to modify the status quo of how we measure these things in order to capture the full value of that."

Marks said two of the greatest challenges the nation faces are restoring global economic competitiveness and the skyrocketing costs of medical care, which has become perhaps the biggest obstacle to long-term economic strength.

"Obesity lies right at the center of those challenges," he said. "The way Congress acts to score legislation, using only a 10-year horizon, misses a huge part of the value of preventive efforts."

The authors served in the George W. Bush administration. O'Grady was assistant secretary of Health and Human Services, and co-author James Capretta served as an associate director of the Office of Management and Budget.

MedicalNewsCopyright © 2012 HealthDay. All rights reserved. SOURCES: March 21, 2012, teleconference with: Michael O'Grady, Ph.D., senior fellow for health care research, National Opinion Research Center, University of Chicago, and principal, O'Grady Health Policy, LLC, and James Marks, M.D., senior vice president and director, Health Group, Robert Wood Johnson Foundation; March 21, 2012, Campaign to End Obesity report, Assessing the Economics of Obesity and Obesity Interventions



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By Denise Mann
HealthDay Reporter

TUESDAY, Feb. 21 (HealthDay News) -- The U.S. Food and Drug Administration plans to take a second look at the weight loss pill Qnexa on Wednesday, after initially rejecting it because of concerns about heart problems and possible birth defects.

While effective at reducing weight, the drug, manufactured by Vivus Inc., was denied approval in 2010 because of its potential side effects. An FDA advisory panel will now review two years of data; when advisers last voted on Qnexa, only one year's worth of follow-up data was available.

The drug combines the appetite suppressant phentermine and the anti-seizure/migraine drug topiramate. Phentermine was once widely prescribed as the "phen" part of the fen-phen weight loss drug. This combo was withdrawn from the market after its use was linked to high blood pressure in the lungs and heart valve disease. The problems were related to the "fen" or fenfluramine part of the combination, not the phentermine.

No new weight-loss drug has been approved in the United States in the past 13 years, according to published reports. As it stands, Xenical is the only FDA-approved drug specifically for long-term use -- up to a year -- for weight loss. Xenical is sold over-the-counter as Alli. However, other drugs may be used off label to promote weight loss.

Last April, a study funded by Vivus found that obese patients taking Qnexa lost an average 22 pounds over a year, while also lowering their blood pressure and cholesterol levels.

Dr. Louis Aronne, founder and director of the Comprehensive Weight Control Program at New York-Presbyterian Hospital/Weill Cornell Medical Center in New York City, is cautiously optimistic that Vivus did a good job responding to FDA safety concerns, and that the FDA will give the drug its nod of approval, with some caveats. Aronne was not involved in the trials but has been an adviser to Vivus and other companies developing weight loss medications.

"I am not as pessimistic as most people," he said.

Vivus has reported that Qnexa may increase the risk of cleft lip in babies of women who use the drug while pregnant. Aronne said the birth defect concern could be addressed through education on who should and should not use the new drug.

"We have learned our lessons with weight loss drugs," he said. "They need to be used in the right people under the right circumstances." The heart risks need to be weighed against reductions in heart disease risk factors that come with weight loss, he said.

Qnexa is not any riskier than bariatric surgery, according to Aronne. "The problem is that it can be distributed more widely," he said. He hopes for a compromise that allows the new compound to be prescribed, but not misused. "Once new medications are approved, local medical boards will need to enforce rules and make sure these medications are prescribed appropriately to the right candidates," he said. "We don't want to open up pill mills."

One thing is clear, he said: More options to treat obesity are needed. "For hypertension, there are 120 medications in nine categories," Aronne said. "We need new options and we need to get physicians thinking about obesity and obesity treatments."

Dr. Scott Kahan, an obesity expert at Johns Hopkins University in Baltimore and director of the National Center for Weight and Wellness in Washington, D.C., agreed. He is optimistic about the FDA's upcoming decision on Qnexa. "The weight loss effects are striking and approaching the amount of weight loss over two years that we get with bariatric surgery," he said. "This is really impressive."

More information

Learn more about weight loss medications at the U.S. National Institutes of Health.

MedicalNewsCopyright © 2012 HealthDay. All rights reserved. SOURCES: Louis Aronne, M.D., founder and director, Comprehensive Weight Control Program at New York-Presbyterian Hospital/Weill Cornell Medical Center, New York City; Scott Kahn, M.D., associate director, Johns Hopkins Weight Management Center, Baltimore, and director, National Center for Weight and Wellness, Washington, D.C.



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View Weight Gain Shockers Slideshow Pictures By Randy Dotinga
HealthDay Reporter

SUNDAY, Feb. 19 (HealthDay News) -- A new animal study suggests that a genetic mutation could put certain people at higher risk for becoming obese if they eat high-fat diets.

At the moment, the practical uses of the research seem to be limited, but physicians could conceivably test people for the mutation and recommend that they avoid certain kinds of diets, said study co-author Dr. Gozoh Tsujimoto, a professor at Kyoto University's department of genomic drug discovery science in Japan. It may also be possible, Tsujimoto said, to eventually give people drugs to combat the effects of the mutation.

If that happens, there would be "a new avenue for personalized health care," Tsujimoto said.

Scientists have been busy studying genetic links to obesity that could make some people more prone to gain extra weight. Two-thirds of Americans are either overweight or obese, the U.S. Centers for Disease Control and Prevention estimates. Excess pounds contribute to a variety of diseases, including heart disease and cancer.

In the new study, researchers looked at the component of the body's internal communication system that plays a role in the regulation of appetite and the production of fat cells.

The investigators found that mice that didn't have the component were 10 percent fatter than other mice when all were fed a high-fat diet. Mice without the component also developed higher intolerance to glucose.

Research conducted in animals does not always translate into humans, and much more research is needed. However, the researchers found that Europeans with the genetic mutation, known as GPR120, were more likely to be obese.

"Our study for the first time demonstrated the gene responsible for diet-induced obesity," Tsujimoto said.

According to Tsujimoto, more than 3 percent of Europeans have the trait. The next step for researchers is to study its prevalence in Japanese, Korean and Chinese people.

What can be done with the knowledge from the study?

Tsujimoto said physicians could advise people with the trait to avoid high-fat diets. A test is available to detect the trait and it costs about $200 in Japan, Tsujimoto said.

While medications could potentially be developed that would reverse the effects of the genetic trait, there are no such drugs now, Tsujimoto added.

Ruth Loos, director of Genetics of Obesity and Related Metabolic Traits at Mount Sinai School of Medicine in New York City, said "these findings provide another piece of what turns out to be the very large puzzle that describes the causes of obesity."

Consistent findings in mice and humans have put the trait "more firmly on the obesity map and provides a new starting point for more research into the function of this gene," said Loos.

"This is only the beginning of likely many years of research to disentangle the physiological mechanisms that lie behind the link between this gene and obesity risk," she said. "It is only when we understand the physiology and biology better that one can start thinking of developing a drug."

The study appears online Feb. 19 in the journal Nature.

MedicalNewsCopyright © 2012 HealthDay. All rights reserved. SOURCES: Gozoh Tsujimoto, M.D., Ph.D., professor, department of genomic drug discovery science, Kyoto University, Japan; Ruth Loos, Ph.D., professor and director, Genetics of Obesity and Related Metabolic Traits, Mount Sinai School of Medicine, New York City; Feb. 19, 2012, Nature, online



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People Who Postpone a Snack Craving Have Less Desire for It; Eat Less Over Time, Study Finds

By Kathleen Doheny
WebMD Health News

Reviewed by Laura J. Martin, MD

Jan. 30, 2012 -- Got a craving for chocolate ice cream, greasy chips, or something else that you're trying not to eat?

Postpone it.

People who postpone a snack they crave actually desire it less and are able to delay eating it, says researcher Nicole Mead, PhD, an assistant professor at Catolica-Lisbon School of Business and Economics in Portugal.

What's more, they then eat less of that food over the next week, she has found.

One key? Postponing has to be to some vague time in the future.

"When you postpone to some indefinite time in the future, the desire for the food actually decreases," Mead says. She presented her findings at the annual meeting of the Society for Personality and Social Psychology in San Diego.

When a craving hits, people often think they have two choices, Mead says: giving in or resisting.

"If you give up, you are usually feeling guilty," she says. If you resist, you often feel deprived and ''you might overindulge later on."

"We propose a third option: To say to yourself, 'I can have it later.'"

It takes you out of that ''yes-no,'' ''should I or shouldn't I?'' conflict, she says.

Mead tested the strategy using different snack foods.

In one study, she invited 99 men and women to watch film clips. She put a bowl of candies in front of each participant. The participants weren't told what the researchers were actually studying. She assigned them to one of three groups:

One group was told they could eat the candies freely.Another group was asked not to eat them.A third group was told they could have them later.

After the film clip viewing, Mead asked the participants unrelated questions, such as whether the temperature in the room was OK, again to throw them off.

Then she told all of them it was OK to eat the candies. The participants weren't told that the researchers were going to measure how much candy they ate.

The group told not to eat the candies while watching the film ate the most, about a third of an ounce. Those told to eat freely and those asked to postpone each ate about half that amount. The postponing group ate a little less than the eat-freely group.

"We also measured chocolate consumption over one week," Mead says. The postponing group ate chocolate candy only once during the week after the experiment. The group told to eat freely ate it three times. The group told not to eat it at the film viewing ate it about four-and-a-half times.

Mead wanted to see if she would get the same results if she allowed people to choose their strategy. She gave 105 high school students in the Netherlands, average age 15, each a bag of chips. They were randomly assigned to an eating strategy or told to choose their own.

The three strategies:

Eat the chips now if you wish.Do not eat the chips.Don't eat them now, but you can eat them later.

The postponing group ate the least amount of chips, whether they were assigned to that group or chose it, Mead found.

They ate the least amount of chips over the week that followed, too, she says. Those in the postpone group had chips about 2.4 times in the next week. Those in the group told to eat freely had them nearly four times. Those in the group told not to eat chips had them 4.5 times.

"This one-minute manipulation lasted seven days," Mead says.

The postponing gives the mind a cooling-off period, Mead says. It may also take you out of conflict mode, torn between feeling guilty and feeling deprived.

However, she believes the postponement must be nonspecific. Not "I'll have that candy at 3 p.m.," but "I'll have the candy later if I want it."

The key may be postponing without telling yourself when, says Brian Wansink, PhD, John S. Dyson professor of marketing at Cornell University. He is a long-time researcher on eating behavior.

He wasn't involved in the Mead study, but he tested the postpone strategy some years ago.

He told people to postpone to a specific time, and he gave up on that research, he tells WebMD. "It worked OK for people who weren't that eager to have a food," he says. But it didn't seem to combat strong cravings.

Some participants, he remembers, were then watching the clock and thinking of nothing else but the food they craved.

Mead's strategy of postponing to some undefined time in the future, he says, might work well for those who want to watch their weight and avoid certain foods. During postponement, he says, they may actually substitute a healthier food.

Wansink reports receiving research funding from Bel Group (Babybel cheeses), Corn Refiners Association, and Birds Eye Foods.

This study was presented at a medical conference. The findings should be considered preliminary as they have not yet undergone the "peer review" process, in which outside experts scrutinize the data prior to publication in a medical journal.

SOURCES: Nicole Mead, assistant professor, Catolica-Lisbon School of Business and Economics, Portugal.Brian Wansink, PhD, John S. Dyson professor of marketing, Cornell University, Ithaca, N.Y.Society for Personality and Social Psychology, 13th Annual Meeting, Jan. 26-28, 2012, San Diego, Calif.

©2012 WebMD, LLC. All Rights Reserved.



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Does Obesity Cause Pain?

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Study: Obese People Are in Pain More Often, Even if They Are Healthy

By Brenda Goodman, MA
WebMD Health News

Reviewed by Laura J. Martin, MD

Jan. 30, 2012 -- A large new study shows that obesity and pain often go hand in hand. That appears to be true even if an obese person is otherwise healthy.

Researchers say that begs some questions: Can extra pounds cause pain? If so, how does fat make us hurt?

A slew of chronic conditions that cause pain are also more common in people who are overweight and obese. Those conditions include arthritis, depression, fibromyalgia, type 2 diabetes, and back pain.

So the assumption has been that being obese makes a person more likely to have multiple medical problems, and many of these conditions may cause pain.

The new survey, however, which included responses from more than 1 million Americans, found that the relationship between obesity and pain persisted even after researchers tried to account for the influences of other pain-causing health problems.

"Being sick can cause pain, but that doesn't necessarily take care of the relationship between obesity and pain," says researcher Arthur A. Stone, PhD, distinguished professor and vice chairman of the department of psychiatry at the Stony Brook University Medical Center in Stony Brook, N.Y.

The study is published in the journal Obesity.

For the study, researchers relied on data collected by telephone surveys conducted by the Gallup organization from 2008 to 2010.

The majority of survey participants were white (85.1%) and had at least a high school education (94.2%).

Every survey participant was asked to report their height and weight. Based on that information, 36.8% of people in the study fell into the low or normal body mass index (BMI) category, 38.3% were considered overweight, and 24.9% were considered obese.

People were asked if they had experienced physical pain the previous day. They were also asked if they had neck, back, leg, or knee conditions that had caused pain during the last 12 months, or if they'd experienced any other condition that caused recurring pain.

They were also asked about the presence of a variety of other medical conditions, including high blood pressure, high cholesterol, asthma, diabetes, heart attack, and depression. Researchers found that as weight increased, so did the likelihood that a person would be experiencing pain.

Compared to normal-weight people in the survey, people in the overweight group -- those with BMIs between 25 and 29 -- had about 20% more pain. People with BMIs between 30 and 34 had about 68% more pain. Those with BMIs between 35 and 39 had 136% more pain, and those with BMIs over 40 reported having 254% more pain.

As expected, chronic pain conditions accounted for a good portion of those results.

And researchers recognize that the relationships between chronic health problems and pain and obesity are complex. In some cases, it could be that having arthritis makes a person less likely to move around, which makes them more likely to gain weight. In others, it may be that being overweight puts strain on the joints, which leads to joint problems that cause pain.

When researchers accounted for the influences of other health problems and pain causing conditions, being overweight was no longer associated with being in pain.

But people who were obese still reported more pain than those with normal BMIs. Researchers caution that their findings are just an association. They don't prove that fat alone causes pain.

But they mirror a handful of other, smaller studies that have also found links between pain and obesity, even when there were no other chronic conditions to explain the findings.

So they say it makes sense that there might be another mechanism connected to having a lot of fatty tissue or to problems with the body's metabolism that might explain the pain.

The study wasn't able to explain how fat might cause pain.

But Stone says that fat cells are known to make chemicals that increase inflammation. "And we know that inflammation is very closely linked to pain perception, so there's the possibility that there's some connection through that kind of process."

He says those questions will ultimately need to be addressed by other researchers.

SOURCES: Stone, A. Obesity, published online Jan. 30, 2012.News release, Stony Brook University.Arthur A. Stone, PhD, distinguished professor and vice chairman, department of psychiatry, Stony Brook University Medical Center, Stony Brook, N.Y.

©2012 WebMD, LLC. All Rights Reserved.



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FRIDAY, Feb. 3 (HealthDay News) -- A smaller plate won't help you eat less, says a new study that challenges a widely held belief.

"Smaller plates are often recommended as a way of controlling intake, but that simply isn't an effective strategy," senior researcher Meena Shah, a professor of kinesiology at Texas Christian University in Fort Worth, said in a news release. "There was no plate size, weight status, or plate size by weight status effect on meal energy intake."

The study included 10 overweight or obese women and 10 normal weight women who were randomly assigned to have lunch using either a small (8.5-inch) or large (10.8-inch) plate. The women were told to serve themselves and eat until they were satisfied.

The women did this on two different days, using a different-size plate each time.

"It is possible that plate size does not have an impact on energy intake because people eat until they are full regardless of what utensils they are using," Shah said.

She noted that overweight and obese women "reported lower levels of hunger and prospective consumptions before the meals and felt less full after the meals compared to normal weight subjects despite no difference in energy consumption between two groups. This suggests that overweight/obese individuals may have a lower ability to sense hunger and fullness than normal weight adults."

The study was recently published in the Journal of Human Nutrition and Dietetics.

-- Robert Preidt MedicalNewsCopyright © 2012 HealthDay. All rights reserved. SOURCE: Texas Christian University, news release, January 2012



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TUESDAY, Feb. 14 (HealthDay News) -- People who drank water or diet beverages instead of calorie-laden drinks lost 4 to 5 pounds over half a year, according to new research.

The study included 318 overweight or obese people divided into three groups: those who switched to water from high-calorie beverages; those who switched to diet soft drinks; and those who weren't advised to change beverages but were given general information about healthy choices that could help them lose weight (the control group).

Over the six-month study, all three groups had small reductions in weight and waist circumference. But those who switched to calorie-free beverages were twice as likely to lose 5 percent or more of their body weight than those in the control group.

In addition, the investigators found that people who drank mostly water had lower fasting glucose levels and better hydration levels than those in the control group.

Percentage of weight loss and lower blood-sugar levels are important because they're associated with improvements in risk factors for obesity-related chronic diseases, according to study author Deborah Tate, an associate professor of nutrition and of health behavior at the University of North Carolina Gillings School of Global Public Health and member of the Lineberger Comprehensive Cancer Center.

"Substituting noncaloric beverages -- whether it's water, diet soft drinks or something else -- can be a clear and simple change for people who want to lose or maintain weight," she said in a university news release. "If this were done on a large scale, it could significantly reduce the increasing public health problem of obesity."

The study appears online and in the March print issue of the American Journal of Clinical Nutrition.

Weight loss among the participants in this study was less than that seen in more intensive, clinic-based behavioral lifestyle modification programs, the researchers said. However, they noted that asking people to change just one part of their diet (in this case, beverages) is consistent with previous findings recommending small but potentially more sustainable lifestyle changes to improve health.

"Substituting specific foods or beverages that provide a substantial portion of daily calories may be a useful strategy for modest weight loss or weight gain prevention," Tate said. "Beverages may be ideal targets, but keep in mind, the strategy will only work if the person doesn't make up for the lost calories some other way."

-- Robert Preidt MedicalNewsCopyright © 2012 HealthDay. All rights reserved. SOURCE: University of North Carolina at Chapel Hill, news release, Feb. 13, 2012



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FRIDAY, March 2 (HealthDay News) -- Breathing cold air during certain physical activities, such as shoveling snow, increases the body's demand for oxygen, which may put people with heart disease at greater risk for cardiac arrest or death, a new study finds.

"This study can help us understand why cold air is such a trigger for coronary events," Lawrence Sinoway, director of the Heart and Vascular Institute at the Pennsylvania State College of Medicine, said in a university news release. "If you are doing some type of isometric work and you're breathing cold air, your heart is doing more work -- it's consuming more oxygen."

The researchers used a hand-grip test (which involves participants squeezing a handgrip, a move known to increase blood pressure) to study the heart and lung function of healthy adults in their 20s and 60s while exposed to cold and normal air temperatures. The researchers found a discrepancy in supply and demand in the participants' left ventricle -- the part of the heart that receives oxygenated blood -- when cold air was introduced during handgrip exercise. They noted that since the participants' hearts were healthy, they were able to compensate for this change and continue working properly.

People with heart disease, however, may not be able to keep up with the increased demand for oxygen. The findings, recently published in the Journal of Applied Physiology and The American Journal of Physiology, Heart and Circulatory Physiology, could explain why fatal heart attacks peak during the winter.

Matthew Muller, postdoctoral fellow at Penn State's Heart and Vascular Institute, said the results were in line with what they expected. "We thought that oxygen demand in the heart would be higher with cold-air breathing, and we also thought that oxygen supply would be a little bit impaired," he said in the news release. "And that's generally what we found."

-- Mary Elizabeth Dallas MedicalNewsCopyright © 2012 HealthDay. All rights reserved. SOURCE: Penn State, news release, Feb. 28, 2012


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MONDAY, March 12 (HealthDay News) -- Promoting physical activity among young school kids can end up improving their academic performance, a new study suggests.

Italian researchers tracked 138 children aged 8 through 11 who took mental acuity tests under a series of conditions that sometimes involved physical activity and sometimes did not.

"Schoolteachers frequently claim that students lose attention and concentration with prolonged periods of academic instruction," first study author Maria Chiara Gallotta, at the University of Rome, said in a news release. "The key elements of learning, particularly important during development, are attention and concentration. Our study examined the relationship between exertion and the attention and concentration levels of schoolchildren."

The findings appear in the March issue of Medicine & Science in Sports & Exercise.

Over a three-week period, the children sat for three exam sessions of 50 minutes each. Before the first test they had all engaged in some form of physical exertion. Before the second test they had only engaged in academic exercises. And the third time they had participated in both physical and academic activity. All the tests were structured to gauge concentration skills as well as the speed with which the kids responded and the quality of their answers.

The children performed best following either physical activity or academic activity, but less well when both were combined before testing.

Processing speed went up by 9 percent after engaging in some form of mental "exercise" and 10 percent after physical activity. But after a combined physical and mental exertion, testing scores went up by just 4 percent.

Similarly, in terms of concentration skills, pretesting mental activity boosted scores by 13 percent, while physical activity sent scores rising by 10 percent. When both were combined, testing results went up by just 2 percent.

The authors said the lower scores could be due to a rise in stress associated with asking children to exercise both their brains and their bodies in the same time span.

"Our findings," Gallotta said, "suggest that varying types of exertion have different beneficial influences on school children's immediate cognitive performance. While more research is needed, we believe this provides helpful justification for increasing physical activity opportunities in the academic setting."

-- Alan Mozes MedicalNewsCopyright © 2012 HealthDay. All rights reserved. SOURCE: Medicine & Science in Sports & Exercise, March 1, 2012


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(HealthDay News) -- Wearing the proper athletic shoes for your sport or exercise can help protect you against discomfort and injury.

The American Academy of Orthopaedic Surgeons says you should pay attention to these features when shopping for athletic shoes:

Shoes for aerobic exercise need sufficient shock absorption, cushioning, a flexible sole and enough stability.Shoes for court sports need a good sole that is specific to your sport.Shoes for field sports need cleats, spikes or studs, and a cushioned insert.Winter-sport shoes should have a snug fit and plenty of ankle support.Track and field shoes depend on the sport, so it's important to ask your coach about proper shoes.Specialty-sport shoes should fit according to the sport -- for instance, cycling shoes should fit snugly.Outdoor-sport shoes need warmth, good tread and plenty of support.

-- Diana Kohnle MedicalNewsCopyright © 2012 HealthDay. All rights reserved.


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(HealthDay News) -- It's easy to veg out in front of the TV when you're bored or looking to relax. But there are healthier ways to wind down.

The Academy of Nutrition and Dietetics offers these healthier alternatives to television:

Take a stroll to explore nearby scenery.Walk to a friend's house.Cook a healthy, new nutritional recipe for dinner.Join an exercise class.

-- Diana Kohnle MedicalNewsCopyright © 2012 HealthDay. All rights reserved.


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Hand-Cooling Device Lets People Feel More Comfortable When Exercising

By Denise Mann
WebMD Health News

Reviewed by Laura J. Martin, MD

March 13, 2012 -- Cool hands, healthy heart?

A new study shows that cool hands may allow you to exercise for longer periods of time.

Obese women who placed their hands in a cooling device while exercising, such as walking on a treadmill, were able to outlast their counterparts whose held a lukewarm device. The cooling device used was the AVAcore CoreControl device, which cools the palms and pulls heat from the body.

Many people become uncomfortably hot and sweaty during exercise. "Cooling will decrease the fatigue that goes with starting an exercise program and allow you to feel more comfortable when you get fit," says study author Stacy T. Sims, PhD. She is an exercise physiologist and nutrition scientist at Stanford University in Stanford, Calif.

Can't afford the $3,000 price tag attached to this device?

Holding an ice-cold water bottle is a less expensive alternative. "Freeze a bottle of water and take it with you so you have it in your hand as you exercise, and you can drink cold water as it is melting," she says.

The findings were presented at the 2012 American Heart Association (AHA) Epidemiology and Prevention/Nutrition, Physical Activity, and Metabolism meeting in San Diego.

During the 12-week study, 24 women aged 30 to 45 who were considered obese based on their body mass index (BMI) held either the cooling device or the lukewarm comparison device while they exercised. This was not a weight loss study. It was a fitness study designed to get women more comfortable with exercising.

The women who used the cooling device tended to outlast those who did not. More women in the comparison group dropped out of the study because they felt uncomfortable when exercising.

Women in the cooling device group also lost 3 inches off their waist size, had lower resting blood pressure, and had greater exercise heart rates. What's more, women who used the cooling device shaved five minutes off the time it took them to walk 1.5 miles, the study shows. By contrast, women who did not use the cooling device saw no such changes after the three-month study.

"By cooling the hands, you cool the rest of the body," says Jerrold Petrofsky, PhD. He is a professor of physical therapy at Loma Linda University School of Allied Health in Loma Linda, Calif. "The hands are a very important switch to our internal thermostat."

And "anything to keep body temperature down will prolong exercise," he says.

AHA spokesperson Gerald Fletcher, MD, agrees. He is also a professor of medicine in the department of cardiovascular diseases at the Mayo Clinic College of Medicine in Jacksonville, Fla.

"Cool hands make a person feel more comfortable during exercise," he says. Other ways to stay cool include working out in a gym with a fan or air conditioner, drinking cold water, and swimming.

Cooling's benefits may involve more than just the comfort factor. It is possible that cooling results in changes in circulation. "I think it is possible, but we don't know," he says.

These findings were presented at a medical conference. They should be considered preliminary as they have not yet undergone the "peer review" process, in which outside experts scrutinize the data prior to publication in a medical journal.

SOURCES: American Heart Association Epidemiology and Prevention, Nutrition, Physical Activity, and Metabolism meeting, San Diego, Calif., March 13-16, 2012. Gerald Fletcher, MD, professor of medicine-cardiovascular diseases, Mayo Clinic College of Medicine, Jacksonville, Fla. Stacy T. Sims, PhD, exercise physiologist and nutrition scientist, Stanford University, Stanford, Calif. Jerrold Petrofsky, PhD, professor of physical therapy, Loma Linda University School of Allied Health, Loma Linda, Calif.

©2012 WebMD, LLC. All Rights Reserved.


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