Mesothelioma is a cancer associated with exposure to asbestos

Mesothelioma is a cancer associated with exposure to asbestos. Once a realatively obscure disease that meant little to the general public, mesothelioma is now known to be among the most aggressive and difficult to treat tumors oncologists yet have encountered.

The disease most often affects men between the ages of 50 and 70

Statistics show that, because of their work history, the disease most often affects men between the ages of 50 and 70 who were employed in an asbestos-laden environment before asbesto regulations were imposed in the late 1970s. Though women still have a much lower frequency of the disease, cases of second-hand exposure to asbestos has prompted more diagnoses among women, especially those whose male family members worked with asbestos.

Diagnosing mesothelioma

Diagnosing mesothelioma in its early stages can be a challenge even for the most experienced oncologists. Also referred to as asbestos cancer, this rare and aggressive disease is directly related to asbestos exposure. Mesothelioma affects the tissue that surrounds the lungs, heart and abdominal cavity.

Medical professionals and research scientists

Medical professionals and research scientists, however, are constantly exploring new ways to combat the disease. For example, doctors know that some combinations of chemotherapy drugs work better than others and tests developed to ascertain earlier diagnosis of the disease or to monitor those most at risk have arrived on the scene.

Medical professionals and research scientists

Medical professionals and research scientists, however, are constantly exploring new ways to combat the disease. For example, doctors know that some combinations of chemotherapy drugs work better than others and tests developed to ascertain earlier diagnosis of the disease or to monitor those most at risk have arrived on the scene.

The reason someone develops mesothelioma

The reason someone develops mesothelioma is usually the lack of proper protection offered to those who worked with asbestos. Though the dangerous properties of asbestos and asbestos products have been evident for decades, many employers neglected to protect their workers from inhaling asbestos while on the job.

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FRIDAY, March 2 (HealthDay News) -- Breathing cold air during certain physical activities, such as shoveling snow, increases the body's demand for oxygen, which may put people with heart disease at greater risk for cardiac arrest or death, a new study finds.

"This study can help us understand why cold air is such a trigger for coronary events," Lawrence Sinoway, director of the Heart and Vascular Institute at the Pennsylvania State College of Medicine, said in a university news release. "If you are doing some type of isometric work and you're breathing cold air, your heart is doing more work -- it's consuming more oxygen."

The researchers used a hand-grip test (which involves participants squeezing a handgrip, a move known to increase blood pressure) to study the heart and lung function of healthy adults in their 20s and 60s while exposed to cold and normal air temperatures. The researchers found a discrepancy in supply and demand in the participants' left ventricle -- the part of the heart that receives oxygenated blood -- when cold air was introduced during handgrip exercise. They noted that since the participants' hearts were healthy, they were able to compensate for this change and continue working properly.

People with heart disease, however, may not be able to keep up with the increased demand for oxygen. The findings, recently published in the Journal of Applied Physiology and The American Journal of Physiology, Heart and Circulatory Physiology, could explain why fatal heart attacks peak during the winter.

Matthew Muller, postdoctoral fellow at Penn State's Heart and Vascular Institute, said the results were in line with what they expected. "We thought that oxygen demand in the heart would be higher with cold-air breathing, and we also thought that oxygen supply would be a little bit impaired," he said in the news release. "And that's generally what we found."

-- Mary Elizabeth Dallas MedicalNewsCopyright © 2012 HealthDay. All rights reserved. SOURCE: Penn State, news release, Feb. 28, 2012


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